The Evaluation of Sodium Lauryl Sulphate in Toothpaste on Toxicity on Human Gingiva and Mucosa: A 3D in vitro Model
نویسندگان
چکیده
of SLS in marketed toothpastes would alter the morphology and biochemical properties (viability and inflammatory cytokine release) of human 3D cell cultures. Since tissue cell cultures are generally recognised in the literature as being a sensitive method of assaying the cytotoxic potential of test materials [16-18], the objective of this experiment was to measure the toxicity of 5 marketed toothpastes on a reconstituted human oral and gingival epithelium model. The working hypothesis was that toothpastes containing SLS showed more negative effects on cell cultures.
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